megaloblastic anemia


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Related to megaloblastic anemia: macrocytic anemia, aplastic anemia

megaloblastic anemia

[¦meg·ə·lō¦blas·tik ə′nē·m̄e·ə]
(medicine)
Anemia characterized by the occurrence of megaloblasts in the bone marrow and blood.
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12] deficiency is often detected because of the megaloblastic anemia that results.
They also pointed out that reversible cytogenetic abnormalities have been observed with megaloblastic anemia, even including karyotypes typically associated with MDS or AML.
12] levels should be considered, particularly when the patient is asymptomatic and there is no evidence of megaloblastic anemia.
DARAPRIM iscontraindicated in patients with known hypersensitivity to pyrimethamine or to any component of the formulation and in patients with documented megaloblastic anemia due to folate deficiency.
12] is important in the differential diagnosis of megaloblastic anemia (1).
22) deficiency (n = 10) among young relatives of patients; (b) Marfan phenotype (n = 5); (c) stroke [(n = 53): ischemic infarct and (or) thrombosis (n = 38); hemorrhage (n = 13) and MELAS syndrome (n = 2)]; (d) megaloblastic anemia (n = 1); Group 2: secondary abnormalities: (a) well-controlled diabetes mellitus without renal failure (n = 135); (b) renal failure [(n = 13): nephrotic syndrome (n = 7), cystinuria--lysinuria (n = 2) and Fanconi syndrome: cystinosis (n = 1), Lowe syndrome (n = 2), and tyrosinemia type I (n = 1)], and (c) anorexia nervosa (n = 43).
Hypokalemia and sudden death may occur in severe megaloblastic anemia which is treated intensely with vitamin B[sub.
Serum transferrin receptor in the megaloblastic anemia of cobalamin deficiency.