Melanosis

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Related to melanotic: melanotic schwannoma, melanotic macule

Melanosis

 

the intensified formation and deposit in organs and tissues of a dark brown or black pigment of the melanin group (normally present in the skin, retina, and meninges).

A distinction is made between congenital melanosis and acquired melanosis. The former includes congenital melanosis of the skin (melanoderma), manifested by freckles or pigmented birthmarks. Acquired melanosis frequently develops as a result of a change in endocrine function (adrenal, pituitary, or gonadal). The pigmentation may be diffuse (for example, in Addison’s disease) or circumscribed (for example, during pregnancy, on the face and around the nipples). The condition may also be caused by systemic poisoning by hydrocarbons (toxic melanoderma) or by physical, mechanical, or chemical irritation (light, heat, the distillate products of coal).

References in periodicals archive ?
We report the case of a 25-year-old male kidney donor who was referred to our centre for an unusually coloured kidney with normal function, but with a diagnosis of melanotic kidney.
A clinicopathologic and immunohistochemical analysis of melanotic neuroectodermal tumor of infancy.
Comparative decreases in tyrosinase, TRP-1, TRP-2, and Pmel 17/silver antigenic proteins from melanotic to amelanotic stages of syngeneic mouse cutaneous melanomas and metastases.
Immunohistochemical and ultrastructural comparative study of external lamina structure in 31 cases of cellular, classical, and melanotic schwannomas.
Multiple melanotic skin lesions were noted, however no cutaneous malignant melanoma was observed.
The metastases may be anywhere in the heart; usually melanotic metastases invade the walls of all 4 cardiac chambers and also the epicardium and endocardium (Figures 18 and 19).
These results are consistent with the prerequisite of melanotic cells, i.
McCune-Albright syndrome occurs when fibrous dysplasia is accompanied by the appearance of scattered areas of melanotic skin pigmentation (cafe-au-lait spots) and sexual precocity.
Conjunctival pallor was noted, and she was found to have melanotic stools.
In our case, there was no history of a current or prior melanotic skin lesion, and there was no other organ involvement on computed tomography imaging or bone scintigraphy scan.
In fact, lentigo maligna also has been called Hutchinson melanotic freckle and melanosis circumscripta precancerosa Dubreuilh.
Blue nevi and other melanotic lesions of the prostate: report of 3 cases and review of the literature.