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Melanosis
(redirected from melanotic)

   Also found in: Dictionary/thesaurus, Medical 0.01 sec.
Melanosis 

the intensified formation and deposit in organs and tissues of a dark brown or black pigment of the melanin group (normally present in the skin, retina, and meninges).

A distinction is made between congenital melanosis and acquired melanosis. The former includes congenital melanosis of the skin (melanoderma), manifested by freckles or pigmented birthmarks. Acquired melanosis frequently develops as a result of a change in endocrine function (adrenal, pituitary, or gonadal). The pigmentation may be diffuse (for example, in Addison’s disease) or circumscribed (for example, during pregnancy, on the face and around the nipples). The condition may also be caused by systemic poisoning by hydrocarbons (toxic melanoderma) or by physical, mechanical, or chemical irritation (light, heat, the distillate products of coal).



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It is extremely important to search clinically for the more common melanotic lesions of the skin, eye, and mucus membranes before making the rare diagnosis of PMME.
Melanotic neuroectodermal tumor of infancy is a rare, neural-crest-derived neoplasm that is believed to be congenital.
A Distinct Lesion of Uncertain Histogenesis Primary intracranial pigmented neoplasms are rare and include melanoma, melanocytoma, melanotic ependymoma, and subependymoma[1]; pigmented choroid plexus papilloma and carcinoma[2-5]; and melanotic astrocytoma.
 
 
 
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