The Rotterdam and Prospect studies have shown that food-derived vitamin K (such as from cheeses) improves long-term cardiovascular health outcomes because it more specifically delivers the long-chain menaquinones
MK-6, 7, 8, and 9.
The role of menaquinones
(vitamin K2) in human health.
Vitamin K Vitamin K is a Required for the (naphthoquinone) quinone compound in formation of the human body in a prothrombin (an storage form as essential component menaquinone
(MK); of blood clotting).
3), (9) Furthermore, it has been demonstrated that long-chain menaquinones
(vitamin K2) are the preferred form of vitamin K for combating age-related diseases, owing to their preferential distribution to the extrahepatic tissues.
, and a synthetic form, menadione.
13]C-labeled acetate (for the MVA pathway) on the formation of menaquinone
(a primary metabolite) and naphterpin (a secondary metabolite).
Atherosclerosis has published a long-term study that explored the relationship between intake of phylloquinone and menaquinones
(vitamins K1 and K2, respectively) and risk of peripheral arterial disease (PAD).
MK-7 is the primary menaquinone
found naturally in fermented foods.
Vitamin k2, a naturally occurring menaquinone
, exerts therapeutic effects on both hormone-dependent and hormone-independent prostate cancer cells.
Natto K2 is a newly available proprietary extract of natto that provides the highly bioavailable form of vitamin K2 as menaquinone
A 2006 meta-analysis of 13 randomized controlled trials that gave phytonadione (Vitamin K1) and menaquinone
(Vitamin K2) supplements for longer than 6 months reported data on bone loss and fracture rates.
Vitamin K ([phylloquinoneK 1], menadione [[kappa]3], menaquinone
[[kappa]2], phylloquinone [2-Me-3 phytyl-1-4 napthoquinone] sourced from plants, menaquinone
[2-M3-3-polyisoprenyl-1-4-naptoquinone] bacterial source) plays a major role in calcium metabolism, blood clotting, and sphingolipid metabolism, but is best known for its role in blood clotting.