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That part of the mesoderm from which all connective tissues, blood vessels, blood, lymphatic system proper, and the heart are derived.



the embryonic connective tissue in the majority of multicellular animals and man.

In the early stages of embryonic development, mesenchyme consists of motile dendriform cells. Most of these cells later lose their motility and unite by their processes into a network (syncytium) or form local aggregates. The mesenchyme originates from cells that have migrated from various germ layers. For example, the chief source of the mesenchyme in coelenterates, worms, and mollusks is the ectoderm (often also the endoderm), and in chordates and echinoderms, the mesoderm. Mesenchyme that originates from endoderm and mesoderm is called endomesenchyme, and mesenchyme originating from ectoderm (the material of the neural columns), ectomesenchyme. In vertebrates and man, endomesenchyme gives rise to various forms of connective tissue in the adult, formed elements of the blood, blood vessels, and smooth muscles. Almost the entire visceral skeleton (the auditory ossicles, gill arches), the pigment cells, and part of the derma are formed from ectomesenchyme.

The poorly differentiated connective-tissue cells (fibroblasts and reticular cells) found in animals and man during the postembryonic period are sometimes called mesenchyme.


Tokin, B. P. Obshchaia embriologiia, 2nd ed. Leningrad, 1970.


References in periodicals archive ?
Assessment of cytotoxicity of pure Imidazole using bone marrow mesenchymal stem cells
Grant, "MR contrast and biological impacts of intracellular superparamagnetic iron oxides on human mesenchymal stem cells with long-term culture and hypoxic exposure," in Melbourne, Australia, 2012, .
Inflammatory fibroid polyps are mesenchymal lesions occurring throughout the digestive tract, especially in the stomach and small intestine; (2) to our knowledge, only 1 case has been reported so far in the gallbladder.
It has been demonstrated that human endometrium contains a low number of EnSCs which seem to belong to the family of the mesenchymal stem cells.
Mesoblast has the worldwide exclusive rights for a series of patents and technologies developed over more than 10 years relating to the identification, extraction, culture and uses of adult Mesenchymal Precursor Cells (MPCs).
Pam Macfarlane, chief executive of the MS Trust, said: While this is a USA trial and not open to people with MS in the UK, it will provide data on the potential of transplanted mesenchymal cells.
Treatment with allogeneic mesenchymal bone marrow cells may offer new hope to patients with chronic neurological or age-related, neurodegenerative diseases.
Preliminary experiments in our laboratory suggest an exciting possibility--that stem cells from hair follicles may be similar to bone-marrow mesenchymal cells," Andreadis underscores.
Toronto is the first place in the world to bank perivascular mesenchymal stem cells from the human umbilical cord and we are extremely pleased to now be able to provide this opportunity to parents across the U.
Chondrogenesis is the process by which a mesenchymal cell--a type of stem cell already assigned to become connective tissue or blood cells--turns into a cartilage cell, or chondrocyte.
Tokyo, Japan, Mar 8, 2006 - (JCN) - The National Institute of Advanced Industrial Science and Technology (AIST) announced on March 7 that its Research Institute for Cell Engineering has established a method to creat a mesenchymal stem cell from tooth germs, in collaboration with Osaka University.
The tumor exhibited cellular features of both basal cell and squamous cell carcinoma and a malignant mesenchymal component that was consistent with malignant fibrous histiocytoma.