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The simple squamous-cell epithelium lining the pleural, pericardial, peritoneal, and scrotal cavities.
The lining of the wall of the primitive body cavity situated between the somatopleure and splanchnopleure.



in vertebrates and man, the epithelial tissue that lines the serous membranes of the body cavity (peritoneum, pleura, pericardium).

Mesothelium is formed from mesoderm. It consists of a single layer of densely arranged flat polygonal cells. In lower vertebrates (cyclostomes, fish, amphibians), mesothelial cells are wholly or partly furnished with cilia. In mammals and man, the surfaces of the cells are covered with microvilli, which assist in the absorption and excretion of cavitary fluid. Mesothelium is highly sensitive to external influences. When the serous membranes are irritated and an inflammatory reaction results, the continuity of the mesothelial layer is interrupted, the cells are destroyed, and the underlying connective tissue is exposed. The connective tissue cells then penetrate the irritated area and phagocytize the dying tissue areas and, in septic inflammation, the bacteria. The connective tissue then proliferates, demarcating the focus of irritation and forming adhesions. Mesothelium grows over the adhesions, preventing them from further development and preventing visceral concrescence.

References in periodicals archive ?
How the mesothelial cell's ability to phagocytize asbestos is known to activate the Nlrp3 inflammasome.
Their scheme divides the cysts into 1) lymphatic origin (simple lymphatic cysts and lymphangioma) 2) cysts of mesothelial origin (benign or malignant) 3) enteric cysts 4) urogenital origin 5) dermoid cysts 6) pseudocysts (trauma or infection).
4) Although somewhat variable, mesothelial tumors often coexpress vimentin and cytokeratins.
Malignant mesothelioma is a neoplasm arising from the mesothelial cells of the serosal surfaces of the pleura and peritoneum.
In tissue culture, North Dakota, Oregon, and Turkish erionite have been found to induce high-mobility group protein B1 (HMGB1) and TNF-alpha release from human mesothelial cells and macrophages, Dr.
The benign mesothelial cell group comprised of six cases of pleuritis/pleural plaque, two cases of pericarditis, one case of multiloculated benign peritoneal inclusion cyst and eight cases of reactive mesothelial proliferation in the context of gynaecological malignancy staging (peritoneal washing).
Video-assisted mediastinoscopy:a useful technique for paratracheal mesothelial cysts.
Antiglycation and antioxidant effect of carnosine against glucose degradation products in peritoneal mesothelial cells.
IL-17 stimulates intraperitoneal neutrophil infiltration through the release of GRO alpha chemokine from mesothelial cells.
Pleural fid analysis was consistent with exudate, with 30,000 red blood cells and 1371 white blood cells consisting of 76% lymphocytes, 18% mesothelial cells, 1% neutrophils, 1% basinophils, and 1% unidentified cells.
MESOTHELIOMA is a cancer of the mesothelial cells which cover the outer surface of most of the body's internal organs.