metabolize

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metabolize

[mə′tab·ə‚līz]
(physiology)
To transform by metabolism; to subject to metabolism.
References in periodicals archive ?
Absorption therefore occurs after these agents are metabolized (hydrolyzed) to bioactive aglycones by intestinal bacteria (Kobashi et al.
This is a significant addition to our intellectual property estate covering key drug-response markers because such a large number of important drugs are metabolized by CYP3A4," notes Kevin Rakin, President and Chief Executive Officer of Genaissance.
Alternatively, since clozapine is also metabolized by the 1A2 isoenzyme of cytochrome P450, some kind of competitive inhibition may have been involved.
Artificial sweeteners used in diet pops are not metabolized by oral bacteria and, therefore, diet pops do not contribute to the caries experience.
Among the many potential applications of this approach is the treatment of HIV and HCV patients with protease inhibitors, which are primarily metabolized by CYP, the gene silenced by AVI-4557.
For example, assume you have a patient with a certain diagnosis that can be effectively treated with both drug X and drug Y, each of which is toxic if it is not metabolized effectively, Currently, because you have no idea how the patient might respond, you may well choose drug X, say, because it happens to be generic.
Phthalates are metabolized and excreted quickly; these metabolites, rather than the parent diesters, are believed to be the active toxicants.
Scientists are striving to understand how fat is metabolized and how excess fat leads to diseases such as diabetes.
Both are prodrugs that must be metabolized in order to release their active ingredients, Marilyn R.
The other potential source of problems lies with the fact that caffeine is metabolized by the 1A2 isoenzyme of cytochrome P450.
Kaletra is metabolized in the liver by cytochrome P450, almost wholly by the CYP3A isoform.
Synthetic hormones act as toxins in the body because they are not metabolized the same way human 'bioidentical' hormones are metabolized.