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metalloenzymes

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metalloenzymes [mə‚talĀ·ō ′en‚zīmz]
(biochemistry)
Metalloproteins that catalyze important cellular reactions.


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The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase.
Zinc is considered a cofactor for over 300 metalloenzymes and one of the symptoms of zinc deficiency is an increased frequency of bacterial and viral infections.
1-3) As a component of enzymes, known as metalloenzymes, zinc participates in the reaction at the active site or provides structural integrity to the enzyme.
 
 
 
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