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Related to metanephric: metanephric adenofibroma, metanephric adenoma, metanephric duct, Metanephric mesenchyme, metanephric cap


One of the posterior of three pairs of vertebrate renal structures; persists as the definitive or permanent kidney in adult reptiles, birds, and mammals.



a paired excretory organ in reptiles, birds, mammals, and man that replaces the mesonephros in the course of embryonic development.

The uriniferous tubules of the metanephros form from the nonsegmented posterior part of the nephrotome; unlike the uriniferous tubules of the mesonephros, they begin at the malpighian corpuscles. The ends of the tubules of the metanephros open not into the wolffian duct, as in the mesonephros, but into the ureter, an outgrowth of it.

References in periodicals archive ?
17] Renal neoplasms are thus classified into renal cell (oncocytoma, papillary adenoma), metanephric, mesenchymal (AML, hemangioma, lymphangioma, leiomyoma, renomedullary interstitial cell tumor), and mixed epithelial and mesenchymal (mixed epithelial and stromal tumor, cystic nephroma) tumors (Table 1).
Of note, all metanephric tumors, which are characterized by an "embryonic" phenotype, display a level of PAX2 expression significantly beyond the already strong staining of other RCC types such as clear cell or papillary RCC, reflecting the pronounced PAX2 expressions during renal embryogenesis.
The kidney derives from the nephric ridge of the intermediate mesoderm where the pro-nephric duct elongates to form the Wolffian duct, which in turn gives rise to the ureteric bud and sets the stage for condensation of metanephric mesenchyme and mesynchemal-to-epithelial cell transition.
CD57 is a useful marker for the diagnosis of metanephric adenoma.
Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice.
4] The embryological anomaly is from premature division of the metanephric bud; the number of kidneys probably reflects the number of abnormal divisions of the progenitor cells.
Solid mixed epithelial and stromal tumors also need to be distinguished from mesoblastic nephroma and metanephric adenofibroma.
2 translocation carcinoma, metanephric adenoma, collecting duct carcinoma, mucinous tubular and spindle cell carcinoma, and chromophobe RCC.
The positivity for cytokeratin 7, cytokeratin 8/18, and vimentin is useful in differentiating papillary RCC from other primary renal neoplasms, including metanephric adenoma, chromophobe RCC, oncocytoma, and urothelial cell carcinoma of the renal pelvis.
Renal cystic diseases (RCDs) and congenital abnormalities of the kidney and urinary tract (CAKUT) comprise a group of metanephric and ampullary bud misadventures and acquired lesions that have captured the interest and challenged the imagination of physicians for centuries.
3-11) These tumors have been published under the following names in the literature: leiomyomatous renal hamartomas, congenital mesoblastic nephroma in an adult, cystic hamartoma of renal pelvis, solitary multilocular cysts of the kidney, multilocular renal cyst with mullerian-like stroma, and adult metanephric stromal tumor.
Dysplastic changes are defined as altered metanephric differentiation during embryogenesis, leading to abnormal kidney.