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methylate |
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The European managers of the DNA Methylation Database have assembled a compendium of known DNA methylations that, although not comprehensive, still provides a useful tool for researchers investigating the roughly 22,000 human genes. Briefly, the metabolic process is carried out in two processes: a) the reactions of reduction that convert the pentavalent species to trivalency, and b) reactions of oxidative methylations where iAs is converted to mono-, di-, and trimethyl arsenic forms (MAs, DMAs, and TMAsO, respectively). This pathway includes-several oxidation state changes, successive oxidative methylations, and at least four metabolites (Vahter 2002). |
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