methylsulfonyl

methylsulfonyl

[¦meth·əl ′səl·fə‚nil]
(organic chemistry)
A functional group with the formula CH3SO2‒. Also known as mesyl.
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References in periodicals archive ?
Pharmacokinetics and metabolism in rats, dogs, and monkeys of the cathepsin K inhibitor odanacatib: demethylation of a methylsulfonyl moiety as a major metabolic pathway.
Abbreviations used: EDTA, ethylenediamine tetraacetate; PAGE, polyacrylamide gel, electrophoresis; PMSF, phenyl- methylsulfonyl fluoride; SDS, sodium dodecyl sulphate
No information was obtained on the methylsulfonyl metabolites.
Distribution of PCB congeners, DDE, hexachlorobenzene, and methylsulfonyl metabolites of PCB and DDE among various fractions of human blood plasma.
Yumoto (1999), "Reduction of Thyroid Hormone Levels by Methylsulfonyl Metabolites of Tetra- and Pentachiorinated Biphenyls in Male Sprague-Dawley Rats," Toxicological Sciences, 48(1):51-54.
Related Products II-17 Dimethyl Sulfone II-17 Various applications of DMSO2 II-17 Dimethyl Sulfide II-17 Methylsulfonyl Methane II-17
In a smaller subset, we measured methylsulfonyl metabolites, but their levels were far lower than the OH-PCBs.
3] concentrations and levels of 14 PCBs, 7 hydroxylated PCBs (HO-PCBs), all methylsulfonyl metabolites of PCBs ([MeSO.
Hydroxylated and methylsulfonyl polychlorinated biphenyl metabolites in albatrosses from Midway Atoll, North Pacific Ocean.
An AOAC Working Group on MSM, chaired by David Lakey, president, Cardinal Nutrition, was created to drive and ensure the development of standardized analytical method(s) for MSM (dimethyl sulfone, also known as methylsulfonyl methane).
Knaus, Design and synthesis of Celecoxib and Rofecoxib Analogues as Selective Cyclooxygenase-2 (COX-2) Inhibitors: Replacement of Sulfonamide and methylsulfonyl pharmacophores by an Azido Bioisostere, J.
The oxidation of 8-(thiomethyl) 4,4-difluoro-3,5- dimethyl-4-bora-3a,4a-diaza-s-indacene 6 with m-CPBA gave methylsulfonyl product 7.