Methyltransferases

(redirected from methyltransferase)
Also found in: Medical, Wikipedia.

Methyltransferases

 

(also transmethylases), enzymes of the class of transferases; they catalyze transmethylation of methyl groups.

Mentioned in ?
References in periodicals archive ?
We will determine the role of each mrna cap methyltransferase in cd8 t cell gene expression during differentiation, Using conditional knock-out mice in conjunction with enzyme biochemistry, Rna sequencing and quantitative mass spectrometry.
Expression levels of SeCys methyltransferase (SMT) in Luobeiqi and KT30 were reduced by Se, while promoted in Defumm-8.
RmtE (RmtE1 and its variant RmtE2) is an uncommon plasmid-mediated 16S rRNA methyltransferase (16S RMTase) found in gram-negative bacteria; only 4 strains have been reported to produce RmtE, all Escherichia coli, including 1 from the University of Pittsburgh Medical Center (Pittsburgh, PA, USA) (1-3).
PRMT5 is a protein methyltransferase that is associated with a number of human cancers.
Their topics include enzyme and protein families that regulate histone modification and cross-talk, targeting DNA methylation, targeting histone lysine methyltransferases in cancer, developments if targeting epigenetic readers, who will benefit from epigenetic drugs, histone methyltransferase activity assays, and safety considerations for epigenetic mechanisms as drug targets: whether existing toxicology studies are fit for the purpose.
9,120,820, claims detection analyte probes based on a natural product mimic of the methyltransferase cofactor S-adenosylmethionine (SAM).
Researchers found that theaflavin-3 (TF-3), the antioxidant, works by inhibiting the function of an enzyme called DNA methyltransferase, which destroys bone tissue.
Researchers found that theaflavin3 (TF3), the antioxidant, works by inhibiting the function of an enzyme called DNA methyltransferase, which destroys bone tissue.
DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation.
In mice, the researchers found that ageing was associated with an increase in hippocampal DNA methyltransferase 3a, a novel DNA methyltransferase that was shown to play a role in cell proliferation and differentiation.
Less common causes are MTHFR deficiency, defects of methionine synthase [involving mutations in 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR, also known as CblG)], and defects in vitamin [B.