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microdialysis

   Also found in: Medical, Wikipedia 0.03 sec.
microdialysis [‚mī·krō·dī′al·ə·səs]
(analytical chemistry)
A technique for sampling biological systems in which a short length of hollow-fiber dialysis membrane is implanted into any tissue or fluid compartment, and through which compounds in the extracellular fluid are collected for subsequent analysis.


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Louis used a method called microdialysis to measure the levels of amyloid-beta protein in the fluid between brain cells of mice.
Published in the journal Science, one of the studies saw microdialysis experiments being conducted on mice, and found that extracellular amyloid-beta levels in the brain fall during slumber and rise with wakefulness.
A model to evaluate the pharmacokinetic and pharmacodynamic variables of extendedrelease products using in vivo tissue microdialysis in humans: Bupivacaine-loaded microcapsules.
 
 
 
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