DM (b) Males, and/or n % CRF, % No myocardial pathologies 14 36 50 Old MI or fibrosis 7 43 29 Recent MI 11 82 18 Recent microinfarct
10 70 40 Healing MI 6 67 50 CHF 10 40 20 Other myocardial pathologies (d) 8 50 50 Sampled Stored >6 days at 4[degrees]C prior to >72 h, death, % % No myocardial pathologies 14 29 Old MI or fibrosis 29 0 Recent MI 27 36 Recent microinfarct
40 10 Healing MI 33 17 CHF 40 20 Other myocardial pathologies (d) 38 25 No.
The finding of even a single microinfarct
in a non-diabetic patient is significant.
The high flow and pressure pulsations in fragile microvasculature and increased energy loss can result in microhemorrhages and microinfarcts
in these organs (8, 21, 22).
High-sensitivity cardiac troponin assays will facilitate the detection of all other non-STEMIs, including so-called microinfarcts
Ischemia, in particular, may cause microinfarcts
that can affect areas of critical inhibition.
Vascular abnormalities such as atherosclerosis, emboli causing microinfarcts
, larger cerebrovascular accident, and vertebrovascular insufficiency are not uncommon causes of both light-headedness and true vertigo.
Occlusion of the arterial blood supply to the subchondral bone from deformed blood cells initiating microinfarcts
has been the proposed mechanism of the sickle cell hemoglobinopathies, of which sickle cell disease is the most common.
The magnetic resonance images (MRIs) from the twins showed lesions indicative of microinfarcts
In addition to or sometimes alone, microvasculature obstruction by thrombi causes disseminated microinfarcts
that quickly produce shock when the major organs, such as heart, liver, brain, and kidneys, are affected.
Dependent upon the extent and degree of obstruction to circulation, there may be scattered microinfarcts
(cotton-wool spots) indicating ischaemia.
Macroscopic infarcts were found in 150 (36%) of the 418 brains that were autopsied for the study, and 110 of those also had evidence of pathologies that can't be detected by conventional imaging, including microinfarcts
, arteriolosclerosis, or both.
This data may implicate that, a poorly grown collateral circulation may not protect against ischemia and probably occurrence of microinfarcts
in the area at risk in patients with chronic total occlusion.