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44) Most institutions do not offer sentinel lymph node evaluation as a routine treatment for DCIS but reserve it for specific patients presenting with high-grade DCIS for which microinvasion is more common, patients to be treated with mastectomy, or patients presenting with large DCIS lesions and a clinically palpable mass.
Interestingly, we found that microinvasion of the thyroid cartilage in the region of the AC was absent in approximately 79% of patients who underwent open surgery after failed radiotherapy.
patients with more extensive disease requiring mastectomy, thus increasing the risk of microinvasion
Concern continues to be expressed about marked interobserver variability in diagnosing microinvasion, with many cases of intraepithelial gland involvement being overinterpreted and the depth of invasion measured by different methods with variable measurement cutoffs.
For instance, MPM did not provide sufficient information to identify microinvasion into lamina propria or invasion in cases with extensive cautery artifact.
Morphologic expressions of urothelial carcinoma in situ: a detailed evaluation of its histologic patterns with emphasis on carcinoma in situ with microinvasion.
An additional 6 cases with an invasive component, classified as either suspicious for invasion, microinvasion ([less than or equal to] 0.
First, small epithelial tributaries adjacent to DCIS (typically high grade) may display a haphazard architectural pattern (Figure 1, A), surrounding stromal sclerosis (Figure 2, A) and/or an inflammatory infiltrate, raising the possibility of microinvasion.
In the final case, deeper sections revealed the presence of cervical microinvasion in a biopsy specimen that had been previously labeled as in situ carcinoma (case 12).
This protocol applies to all invasive carcinomas of the breast, including ductal carcinoma in situ (DCIS) with microinvasion.
Of 265 purported cases of microinvasion submitted to a group of reference pathologists of the GOG, about 50% were rejected.
This protocol applies to ductal carcinoma in situ (DCIS) without invasive carcinoma or microinvasion.
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