4 The application of exfoliated buccal cells for micronuclei
(MN) assay determines the genotoxic potential on the targeted tissues in response to the long-term exposure to cytotoxic as well as genotoxic chemicals.
frequency in peripheral blood lymphocytes of cancer patients: a meta-analysis.
Altamirano-Lozano, "Antigenotoxic effects of (-)-epigallocatechin-3-gallate (EGCG), quercetin, and rutin on chromium trioxide-induced micronuclei
in the polychromatic erythrocytes of mouse peripheral blood," Journal of Toxicology and Environmental Health Part A, vol.
The frequencies of erythrocyte with micronuclei
, notched nuclei, cells with nuclear remnants, blebbed nuclei and binucleated erythrocytes were significantly (Pless than 0.
Investigation of micronuclei
and other nuclear abnormalities in peripheral blood and kidney of marine fish treated with crude oil.
In the present study, DS individuals aged > 11 to [less than or equal to] 21 years showed increased frequency of micronuclei
than younger DS individuals [less than or equal to] 11 years.
in neonates and children: effects of environmental, genetic, demographic and disease variables.
The detection of micronuclei
(MNi) has been widely used for years for the evaluation of mutagenic, clastogenic and aneugenic effects in vivo and in vitro.
2), lobed or notched nuclei along with blebbed membrane nuclei and micronuclei
and other nuclear anomalies in buccal smears: a field test in snuff users.
The buccal micronuclei
cytome assay (BMCyt) is an excellent candidate to serve as a biomarker.
Many authors evaluated mutagenic and genotoxic effects of glyphosate in its Roundup[R] commercial formulation through micronuclei
and comet trials in aquatics organisms (6,8,13,14,16).