Micronucleus

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micronucleus

[¦mī·krō′nü·klē·əs]
(invertebrate zoology)
The smaller, reproductive nucleus in multinucleate protozoans.

Micronucleus

 

in infusorians, the smaller (generative) nucleus. The micronucleus is usually diploid and divides by mitosis; however, during the sexual process in infusorians (conjugation), it divides meiotically and gives rise to sexual nuclei or pronuclei. During the vegetative period, the genetic apparatus of the micronucleus remains inactive, does not synthesize ribonucleic acid, and has no influence on the phenotype of the organism.

References in periodicals archive ?
4 The application of exfoliated buccal cells for micronuclei (MN) assay determines the genotoxic potential on the targeted tissues in response to the long-term exposure to cytotoxic as well as genotoxic chemicals.
Altamirano-Lozano, "Antigenotoxic effects of (-)-epigallocatechin-3-gallate (EGCG), quercetin, and rutin on chromium trioxide-induced micronuclei in the polychromatic erythrocytes of mouse peripheral blood," Journal of Toxicology and Environmental Health Part A, vol.
The frequencies of erythrocyte with micronuclei, notched nuclei, cells with nuclear remnants, blebbed nuclei and binucleated erythrocytes were significantly (Pless than 0.
Investigation of micronuclei and other nuclear abnormalities in peripheral blood and kidney of marine fish treated with crude oil.
In the present study, DS individuals aged > 11 to [less than or equal to] 21 years showed increased frequency of micronuclei than younger DS individuals [less than or equal to] 11 years.
Micronuclei in neonates and children: effects of environmental, genetic, demographic and disease variables.
The detection of micronuclei (MNi) has been widely used for years for the evaluation of mutagenic, clastogenic and aneugenic effects in vivo and in vitro.
2), lobed or notched nuclei along with blebbed membrane nuclei and micronuclei (Fig.
Micronuclei and other nuclear anomalies in buccal smears: a field test in snuff users.
The buccal micronuclei cytome assay (BMCyt) is an excellent candidate to serve as a biomarker.
Many authors evaluated mutagenic and genotoxic effects of glyphosate in its Roundup[R] commercial formulation through micronuclei and comet trials in aquatics organisms (6,8,13,14,16).