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microtubule

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia, Hutchinson 0.02 sec.

microtubule

Tubular structure enclosed by a membrane found within animal and plant cells. Of varying length, they have several functions. They help give shape to many cells and are major components of cilia and flagella, participate in the formation of the spindle during cell division (mitosis), and assist the movement of vesicles from the cell bodies of nerve cells toward the ends of those cells' long extensions (axons) and back to the cell bodies.


microtubule [¦mī·krō′tüb·yül]
(cell and molecular biology)
One of the hollow tubelike filaments found in certain cell components, such as cilia and the mitotic spindle, and composed of repeating subunits of the protein tubulin.


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In earlier work, many specialists in biologically inspired micromotors--including Uyeda's group--used components of cells, such as filaments called microtubules (SN: 10/27/01, p.
Since the compound does not interfere with the formulation of microtubules, it is expected to develops no serious side effects such as nerve disorders.
The distribution of microtubule protein within cultured Sertoli cells was examined using monodonal anti--[alpha]-tubulin at a final dilution of 1:1,000 (Sigma) and fluorescein isothiocyanate-conjugated goat antimouse IgG (Alexa-88; Molecular Probes).
 
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