microtubule-associated protein


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microtubule-associated protein

[¦mī·krō‚tüb·yül a¦sō·sē‚ād·ed ′prō‚tēn]
(cell and molecular biology)
A protein that enhances the rate and extent of the polymerization of intracellular microtubules or that modifies their properties once formed. Abbreviated MAP.
References in periodicals archive ?
These include OCT4 for germinoma, [alpha]-inhibin (inhibin A) and D2-40 for CHB, claudin-1 for meningioma, microtubule-associated protein 2 and neuronal nuclei for MDB, and INI1 for ATRT.
Segregation of a missense mutation in the microtubule-associated protein tau gene with familial frontotemporal dementia and parkinsonism.
In addition, phosphorylation of microtubule-associated proteins (MAPS) and actin-associated proteins may induce alterations of polymerization of MTs and distribution of MFs (30,31).
Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease.
PAR-1 and the microtubule-associated proteins CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles.
Abnormal expression of two microtubule-associated proteins (MAP2 and MAP5) in specific subfields of the hippocampal formation in schizophrenia, Proc.
Since tau, one of the major microtubule-associated proteins in the human brain, is one of the hallmarks of Alzheimer's disease, she focused on the analysis of tau proteins from Alzheimer brain tissue and compared them with the properties of recombinant tau, in an effort to characterize the pathological changes of the protein in the disease.
Other neuronal marker proteins that have been identified in central neurocytoma include neurofilament protein, neuron-associated class III [beta]-tubulin, and microtubule-associated proteins MAP2 and tau.

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