microtubule-associated protein


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microtubule-associated protein

[¦mī·krō‚tüb·yül a¦sō·sē‚ād·ed ′prō‚tēn]
(cell and molecular biology)
A protein that enhances the rate and extent of the polymerization of intracellular microtubules or that modifies their properties once formed. Abbreviated MAP.
References in periodicals archive ?
Abbreviations: hepatocellular carcinoma, HCC; dietary supplement, DS; focal adhesion kinase, FAK; transforming growth factor beta, TGF-[beta]; nuclear factor kappa-light-chain-enhancer of activated B cells, NF-[kappa]B; activator protein 1, AP-1; 3-(4,5-dimethyithiazol-2-yl)-2,5-diphenyltetrazolium bromide, MTF; bafilomycin A1, BafA1; 4'-6-diamidino-2-phenylindole, DAPI; Dulbecco's modified Eagle's medium, DMEM; fetal bovine serum, FBS; polyvinylidene difluoride, PVDF; acidic vesicular organelles, AVOs; poly (ADP-ribose) polymerase, PARP; microtubule-associated protein 1A/1B-light chain 3, LC3; mitogen-activated protein kinases, MAPK.
3]R: Inositol triphosphate receptor IRE1[alpha]: Inositol-requiring enzyme 1 alpha MAM: Mitochondria-associated membrane MAP LC3: Microtubule-associated protein light chain 3 Mfn2: GTPase mitofusin 2 MMP: Mitochondrial membrane potential MPTP: Mitochondrial permeability transition pore NFT: Neurofibrillary tangles PACS-2: Phosphofurin acidic cluster sorting protein 2 PDI: Protein disulfide isomerase PERK: Protein kinase R- (PKR-) like ER kinase RNS: Reactive nitrogen species ROS: Reactive oxygen species RyR: Ryanodine receptor TOM: Transporter outer membrane TIM: Transporter inner membrane UPR: Unfolded protein response VDAC: Voltage-dependent anion channel XBP-1: Xbox binding protein 1.
Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/ p38delta at Thr50 promotes microtubule assembly.
82) Microtubule-associated protein 2 antibody mirrors synaptophysin but has a more intense granular or punctate pattern of reactivity.
JNK exerts its effects on the cytoskeleton by phosphorylating numerous microtubule-associated proteins (MAPs) such as MAP2, MAP1B, tau and the stathmin family microtubule-destabilizing protein SCG10.
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands.
In addition, phosphorylation of microtubule-associated proteins (MAPS) and actin-associated proteins may induce alterations of polymerization of MTs and distribution of MFs (30,31).
Washington, Dec 17 (ANI): Different varieties of a-synuclein gene and its interaction with the microtubule-associated protein tau (MAPT) H1 haplotype can influence the speed of clinical deterioration in patients with Parkinson's disease, a new study has found.
The major component of these filaments is the microtubule-associated protein [tau], a normal protein that occurs in a modified, hyperphosphorylated form in AD.
10; Microtubule-Associated Protein Tau and AD7C-Neural Thread Protein are Elevated in Cerebrospinal Fluid of Alzheimer's Disease Patients: Influence of Genetic Risk Factors.
Characterization of smooth muscle caldesmon as a microtubule-associated protein.
Indianapolis, Indiana); (4) monoclonal anti-tau microtubule-associated protein (anti-tau) at a 1:100 dilution of the 1 mg/ml stock solution (clone Tau 1; Boehringer Mannheim Corp.

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