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Granuloma
(redirected from midline granuloma)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
granuloma [‚gran·yə′lō·mə]
(medicine)
A discrete nodular lesion of inflammatory tissue in which granulation is significant.
Granuloma 

a focal growth of inflammatory origin in the cells of young connective tissue in the form of a small node.

Granuloma develops in connection with various (most often infectious) processes (tuberculosis, syphilis, leprosy, brucellosis, tularemia, actinomycosis), with collagenic diseases (such as rheumatism), and at the sites of entry of foreign bodies. Certain granulomas have more specific names, such as the tubercle in tuberculosis and the gumma in syphilis.
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Discussion Because malignant lymphomas are associated with surface crusting, widespread necrosis, and inflammation, they were once considered to be inflammatory lesions, known as lethal midline granulomas or nonhealing granulomas.
Sinonasal lymphoma: a case report by Agarwal, Salil / Ear, Nose and Throat Journal
5,6) Other differential diagnoses include intracranial astrocytoma or meningioma with nasal extension, neuroglial heterotopia, lymphoma/plasmacytoma, esthesioneuroblastoma, angiofibroma, lethal midline granuloma and, rarely, carcinoid tumor.
Nasal glioma (neuroglial heterotopia) mimicking an astrocytoma: case ... by Hashemi, Seyed Baseer / Ear, Nose and Throat Journal
In 1995, Sevinsky et al described a case of total nasal septal destruction and a necrotic ulcer on the philtrum that mimicked a midline granuloma.
Cocaine-induced oronasal fistulas with external nasal erosion but ... by Kass, Erik S. / Ear, Nose and Throat Journal
 
 
 
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