minus strand


Also found in: Medical.

minus strand

[′mī·nəs ‚strand]
(cell and molecular biology)
A polynucleotide strand that is complementary to, and formed by transcription from, another specific polynucleotide (plus) strand, with which it produces the double-stranded (double-helix) ribonucleic acid.
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References in periodicals archive ?
By virtue of the orientation of the associated cas genes, the locus is situated on the minus strand, whereas its spacers are numbered within the locus, not the genome.
The claims also cover siRNAs targeting the plus and the minus strands of the virus and the genes encoded by the viral genome.