(redirected from mitochondrial encephalopathy)
Also found in: Dictionary, Thesaurus, Medical.
Related to mitochondrial encephalopathy: MELAS syndrome


Any disease of the brain.



a collective term that designates a noninflammatory organic disease of the brain. Some encephalopathies are innate, resulting from embryopathy. Others are the result of infection, poisoning, trauma, or vascular disease of the brain. There are no specific manifestations. The most common encephalopathies resemble neuroses (asthenia, irritability, insomnia, headaches) or psychoses (narrowed scope of interests, passivity, emotional instability, vulgarity). Symptoms may include memory loss or mental deterioration.

Alcoholic encephalopathies are alcoholic psychoses. They may be acute, as in Wernicke’s encephalopathy (named for the German neuropathologist C. Wernicke, who described the condition in 1881), or chronic, as in Korsakov’s psychosis (named for S. S. Korsakov) and alcoholic pseudoparalysis. Lead encephalopathy is caused by chronic poisoning by lead salts.

Treatment for encephalopathies depends on the cause of the disease.

References in periodicals archive ?
Abstract: Mitochondrial encephalopathy with lactic acidosis and stroke-like syndrome (MELAS) is a progressive neurodegenerative disorder frequently complicated by diabetes mellitus and sensory neuronal hearing loss.
The most common point mutation is the A3243G mutation in tRNA leu(UUR), which is responsible for mitochondrial encephalopathy lactic acidosis, and stroke-like episodes (MELAS) syndrome and maternally inherited diabetes and deafness (MIDD).
The developmental pediatrician gave him a diagnosis of cerebral palsy secondary to probable mitochondrial encephalopathy.

Full browser ?