mitogen


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mitogen

[′mīd·ə‚jen]
(cell and molecular biology)
A compound that stimulates cells to undergo mitosis.
References in periodicals archive ?
Results suggest an influence of compounds on cytokine cascades which are elicited by the mitogen PHA and are involved in the induction of IDO with the breakdown of tryptophan as well as the formation of neopterin.
Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.
In vitro mitogen stimulated T cell proliferation, using human whole blood cell cultures, was measured following the method of Kramer and Burri.
A mitogen causes cells to pro-liferate, that is, to multiply through division.
T-cell subset levels and results of mitogen stimulation studies were also normal.
Mitogen activated protein kinases (MAPK) have been linked to hyperoxia toxicity in both cell cultures and animal models.
Cells were tested in triplicate for each unstimulated control (containing only media 1 or 2, respectively) and each mitogen concentration with final volumes at 200 [micro]L/well for mitogens in media 1 and 100 [micro]L/well for mitogens in media 2.
The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus.
The mitogen phytohemagglutinin is used as an assay control and saline as a negative control or "nil antigen.
Binding of RANKL to RANK leads to the activation of signaling modules such as NF-kappa B, mitogen activated protein kinases (MAPK's), protein kinase C (PKC), Ca2+/Calcineurin/nuclear factor of activated T cells (NFAT) and phosphatidyl 3-kinase (PI3K).
Fabaceae) on mitogen response of the spleen cells in Graffi tumor bearing (GTBH) and healthy hamsters were reported.

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