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molecular mimicry

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molecular mimicry [mə′lek·yə·lər ′mim·i‚krē]
(immunology)
The sharing, by two organisms closely related ecologically but not phylogenetically, of common macromolecular structures that are not attributable to evolutionary conservation of these structures.


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Shoenfeld and colleagues "suggest that molecular mimicry mechanism between the pathogen and the [[beta]2-glycoprotein l] molecule may be the cause of [antiphospholipid antibody syndrome].
The book describes the use of oils and magnetic fields to grow better quality protein crystals, deals with the use of bioinformatics and mass spectrometry in crystallomics, and discusses the role of molecular mimicry and the structure of amyloid proteins and myelin proteins in diseases such as Alzheimer's disease and multiple sclerosis.
As Gallo put it at an AIDS conference last summer: "The molecular mimicry in which HIV imitates components of the immune system sets events into motion that may be able to proceed in the absence of further whole virus.
 
 
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