molecular recognition

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Molecular recognition

The ability of biological and chemical systems to distinguish between molecules and regulate behavior accordingly. How molecules fit together is fundamental in disciplines such as biochemistry, medicinal chemistry, materials science, and separation science. A good deal of effort has been expended in trying to evaluate the underlying inter-molecular forces. The weak forces that act over short distances (hydrogen bonds, van der Waals interactions, and aryl stacking) provide most of the selectivity observed in biological chemistry and permit molecular recognition. The recognition event initiates behavior such as replication in nucleic acids, immune response in antibodies, signal transduction in receptors, and regulation in enzymes. Most studies of recognition in organic chemistry have been inspired by these biological phenomena. It has been the task of bioorganic chemistry to develop systems capable of such complex behavior with molecules that are comprehensible and manageable in size, that is, with model systems. See Antibody, Chemoreception, Enzyme, Nucleic acid, Synaptic transmission

molecular recognition

[mə¦lek·yə·lər ‚rek·ig′nish·ən]
(cell and molecular biology)
The ability of biological and chemical systems to distinguish between molecules and regulate behavior accordingly.
The (molecular) storage and the (supramolecular) retrieval and processing of molecular structural information and interactions.
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References in periodicals archive ?
Objective: Time-resolved THz-Calorimetry Explores Molecular Recognition ProcessesDefinition: THz-calorimetry is the science of measuring low frequency density of states kinetics for the purpose of deriving the entropy changes associated with biological processes in real time.
In order do this, we utilize a molecular recognition element called tentacle probes (TP), which are unique elements that use divalent binding to achieve results of high sensitivity as well as extremely high specificity without false positives.
The plant was designed for the purpose of testing the use of Molecular Recognition Technology (MRT) for the separation of rare-earth elements at bulk scale.
This is achieved by leveraging genetic engineering and molecular recognition concepts.
Molecular recognition and self-assembly properties of macrocyclic compounds have been extensively investigated because of their extensive applications in drug delivery, nanotechnology, and separation techniques [1-3].
Molecular imprinting is a tool for synthesizing tailor-designed molecular recognition sites in polymers structured at micrometer and nanometer scales.
Our biosensor test uses a new molecular recognition tool that works like a lock that only fits one key; it picks out the ball-shaped amyloid clusters without detecting the individual amyloids.
In their article entitled "The case for intrinsically disordered proteins playing contributory roles in molecular recognition without a stable 3D structure" (http://f1000.
This equilibrium geometry, with its equilibrium bond angles and bond lengths, results in properties like molecular size, molecular shape, molecular recognition, reactivity, etc.
The idea is to take something we normally think of as plastic, and enable it to adopt structures that are more complex and capable of higher function, such as molecular recognition, which is what proteins do really well," said Zuckermann.
This work presents detailed methods and protocols for studying the formation, dynamics, and molecular recognition of G-quadruplex structures.
Siva's research investigates the molecular and supramolecular assembly characteristics of systems to gain a deeper understanding of the interplay between molecular structure, assembly, dynamics and the role of external interactions critical for molecular recognition events in light-initiated reactions.

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