monogenic


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Related to monogenic: monogenic disease

monogenic

[‚män·ə′jen·ik]
(genetics)
Relating to or controlled by one gene.
References in periodicals archive ?
Reduced penetrance is probably the result of modifier genes that are present elsewhere in the genome, and which can now be more easily identified because of the HGP and ENCODE; in turn, these modifier genes can be used to increase predictive precision in the form of modifier gene-complemented monogenic diagnostic tests.
Other therapeutic programs are focused on monogenic diseases, including hemophilia and hemoglobinopathies, and Parkinson's disease.
Keywords in this release: gene therapy, Gendicine, electroporation, combination trials, viral vectors, 'naked' deoxyribonucleic acid, DNA, monogenic, oncology, research, information, market, trends, technology, service, forecast, market share
This molecular counting strategy can, in principle, be applicable to all forms of monogenic diseases, namely paternally or maternally inherited, autosomal dominant diseases and autosomal recessive diseases with any combination of parental mutations.
This molecular counting strategy can in principle be applicable to all forms of monogenic diseases, namely paternally or maternally inherited autosomal dominant diseases and autosomal recessive diseases with any combination of parental mutations.
Other therapeutic development programs are focused on macular degeneration, ischemic heart disease, congestive heart failure, neuropathic pain, and infectious and monogenic diseases.
We will continue to leverage the potential of this strategy for development of ZFP Therapeutics for other monogenic diseases, and remain on track to file IND applications for the hemophilia B program and the first of our lysosomal storage disorder programs by the end of 2015.
The second half of the text covers applications in more detail and offers chapters on quantitative analyses of DNA methylation, mitochondrial DNA analysis, real-time immuno-PCR, clinical microbiology and virology, solid organ transplant modeling,real-time-PCR applications in hematology, and prenatal diagnosis of monogenic disease caused by single nucleotide changes.
Other therapeutic development programs are focused on diabetic neuropathy, ischemic heart disease, congestive heart failure, cancer, neuropathic pain, and infectious and monogenic diseases.
Gene Mapping Center at Max Delbruck Center for Molecular Medicine The Gene Mapping Center is a specialised laboratory for high throughput genotyping for gene mapping in monogenic as well as complex diseases.
We will also continue to leverage the potential of our powerful IVPRP for development of ZFP Therapeutics for other monogenic diseases, and remain on track to file Investigational New Drug (IND) applications for the hemophilia B program and the first of our lysosomal storage disorder programs by the end of 2015.