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The transformation involved in the growth and differentiation of cells and tissue. Also known as topogenesis.



the rise and development of organs, systems, and parts of organisms in their individual development (ontogeny), as well as in their historical, or evolutionary, development (phylogeny). The study of morphogenesis is one of the principal areas of plant, animal, and human morphology.

The established lawlike regularities of morphogenesis provided important evidence for the evolution of organisms. Contributors to the study of morphogenesis [followed by the years in which they made important discoveries] were Aristotle (fourth century B.C.), P. Belon (1555), W. Harvey (1651), C. F. Wolff (1759), J. W. von Goethe (1790, 1795), E. Geoffrey SaintHilaire (1831), K. E. von Baer (1828–37), W. Hofmeister (1851), E. Haeckel (1866), I. N. Gorozhankin (1875, 1880), and A. N. Severtsov (1931, 1939).

The study of morphogenetic features at various stages of ontogeny for the purpose of controlling the development of organisms is a basic concern of developmental biology, genetics, molecular biology, and evolutionary physiology. Morphogenetic research is also important in the study of heredity.


Shmal’gauzen, 1.1. Reguliatsiia formoobrazovaniia v individual’nom razvitii. Moscow, 1964.
Sinnott, E. Morfogenez rastenii. Moscow, 1963. (Translated from English.)
Waddington, C. Morfogenez igenetika. Moscow, 1964. (Translated from English.)


References in periodicals archive ?
FRT development is similar in most mammals, although the timing of morphogenesis differs among species.
After light organ colonization, fragments of PGN and another bacterial envelope component, lipopolysaccharide, act in synergy to induce the morphogenesis of the ciliated epithelial fields on the surface, a process that culminates in the complete regression of the epithelial appendages by 96 h (Fig.
Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis.
2D cell culture studies have provided many insights into cell development, disease pathology, tissue morphogenesis and other areas.
Keywords: Ammonium nitrate, inflorescence, morphogenesis, plant growth regulators, sucrose.
In contrast, branching morphogenesis occurs in mice postnatally, and the lobe-specific branching patterns are complete between 15 and 20 days of age [15].
The second point is more contentious and is the debate of "top-down" versus "bottom up" morphogenesis in the histogenetic origination of colonic tubular adenoma.
In addition hair follicle morphogenesis was also altered in the treated group; they were reduced in number and their growth was arrested at germ stage of hair follicle development.