The visuo-cognitive and motor effect
of amantadine in non-Caucasian patients with Parkinson's disease.
The maximum motor effect
is reached 60 min after L-DOPA administration.
Parkinson's disease (PD) was first described in 1817, but it was not until the mid-20th century that loss of dopaminergic neurons in the basal ganglia was identified as the primary cause of the motor effects
considered the cardinal signs of PD.
Initiation of a hypnotic effect is approximately 20 minutes; therefore BZRAs must be taken when already in bed to avoid amnesia and motor effects
Other confounding factors can further complicate diagnosis, including an insidious onset, slow progression, motor effects
of Parkinson's disease, and whether the impairment is the result of cognitive dysfunction, he said.
I'm not surprised that they showed the motor effects
as more robust, because at an early age that's mostly what one sees," says Edward Levin, a professor of psychiatry and psychological and brain sciences at Duke University.
Importantly there is only one current drug on the market for Parkinson's dementia, and none that can address both the motor effects
and the dementia effects.
Depression often accompanies Parkinson's disease, but some clinicians have been reluctant to use SSRIs because of fear of exacerbating the motor effects
of Parkinson's disease.
Pollak P, Limousin P, et al: Modifications of the stimulation site within GPi induce different motor effects
in parkinsonian patients.
We are gratified that the SOM201 study met the primary endpoint for wake after sleep onset (WASO) with no unwanted next-day cognitive or motor effects
In early clinical data, licensed by Orphan Medical, epidurally delivered Butamben appeared to be highly selective in blocking pain transmission with no residual sensory or motor effects
In general, tolerance to motor effects
and reduction of body temperature were greater in adolescents than in adults (148).