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multimer |
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multimer [′məl·tə·mər] (biochemistry) A protein molecule composed of two or more monomers. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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A severe deficiency of ADAMTS13 activity can be associated with the accumulation of unusually large multimers of VWF that have increased platelet aggregating potential; these large VWF molecules are assumed to cause the disseminated microvascular platelet-rich thrombi that are characteristic of TTP. Time dependent progressive increase in aggregation produced large multimers, which stayed on top of the gel. Multimer formation and ligand recognition by the long pentraxin PTX3: similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component. |
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