multimer


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Related to multimer: multimeric

multimer

[′məl·tə·mər]
(biochemistry)
A protein molecule composed of two or more monomers.
References in periodicals archive ?
Severe ADAMTS-13 deficiency may result in ultralarge vWF multimers that spontaneously interact with platelet receptors and cause thrombi in microcirculation (14-17).
4) Supplementary laboratory testing may also be performed and include VWF multimers, ristocetin induced platelet agglutination (RIPA), and/or VWF-factor VIII binding (VWF:FVIIIB).
PFA-100, vWF studies, vWF multimers and Ristocetin Induced Platelet Aggregation (RIPA) were repeated with results confirming the previous findings (Table 1) except that vWF parameters were now more significantly reduced but still demonstrated the functional discordance.
In patients with TTP, absent or severely reduced activity of ADAMTS 13 prevents timely cleavage of unusually large multimers of von Willebrand factor as they are secreted by endothelial cells.
Multimer distribution is classically analyzed by gel electrophoresis (6).
Plasma adiponectin consists of trimer (presented as a low molecular weight multimer, LMW, in the present study) and over-hexamer (presented as high molecular-weight multimers, HMW).
Ferritin is a multimer of 24 subunits comprised of two subtypes H (heavy, 21kDa) or L (light, 19kDa) that constitute the central core that contains tip to 4.
coli Occasional Yes O157:H7 Renal failure Uncommon Common Neurologic symptoms Common Uncommon Organ involvement Multiple organs Limited to kidney VWF multimer Ultra-large forms Smaller multimers present predominate ADAMTS-13 activity Deficient Normal
Multimer formation and ligand recognition by the long pentraxin PTX3: similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.
The latter potentially can occur as a paraneoplastic syndrome or be due to degradation of high molecular weight multimers (detectable in a multimer analysis) in cases of mechanical destruction, e.
Altor BioScience Releases STAR Multimer Reagents II-37