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Related to multiple exostoses: Multiple congenital exostoses


A benign cartilage-capped protuberance from the surface of long bones but also seen on flat bones, caused by chronic irritation as from infection, trauma, or osteoarthritis.



a benign bony or bony-cartilaginous growth on the surface of a bone in the form of a linear or round mass. Exostoses develop mainly in males during childhood and adolescence, on the femur, tibia, humerus, and other bones. They cease to enlarge when bone growth ends. They usually do not cause complaints. However, fairly large exostoses compress muscles and nerve trunks, causing pain and hampering movement. The principal means of diagnosing exostoses is by X ray.

Exostoses are removed surgically if symptoms are pronounced or if the exostoses suddenly begin to grow rapidly in adults. Individuals suffering from exostoses are kept under clinical observation.

References in periodicals archive ?
The differential diagnosis of hereditary multiple exostoses includes the enchondromatosis, which are a heterogeneous group of syndromes that present with multiple enchondromas associated with pathological fractures, pseudarthrosis, limb shortening, malignant transformation risk, and scoliosis.
Although there is good literature review published regarding cases of hereditary multiple exostoses, however, only a few cases have been reported in Puerto Rico.
Clinical outcome and genotype in patients with hereditary multiple exostoses.
For example, only 10% of the patients with multiple exostoses have the hereditary form of the syndrome, and only 20% of the patients with WWS have a defect in the POMT1 gene.
Genotype-phenotype correlation in hereditary multiple exostoses.
His achievements are all the more remarkable as he suffers from a bone condition called Hereditary Multiple Exostoses (HME), which affects only around 1,000 people in Britain.
Now 42, the Walkergate mum-of-three has lived with the debilitating bone disorder Hereditary Multiple Exostoses since she was a baby.
Nhereditary Multiple Exostoses (HME, EXT, MHE, Diaphyseal Aclasis, Familial Bony Spurs) is usually, but not necessarily, an inherited condition which can produce bony lumps close to the end of any bone, but particularly those of the limbs
John Simpson and his two teenage boys all suffer from Hereditary Multiple Exostoses, a condition that sees lumps growing on their bones.

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