multiple isomorphous replacement technique

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multiple isomorphous replacement technique [‚məl·tə·pəl ‚ī·sə‚mȯr·fəs ri′plās·mənt tek‚nēk]

(crystallography)

A technique for overcoming the phase problem by growing crystals in three different isomorphic chemical forms and comparing x-ray diffraction data obtained from all three. Abbreviated MIR technique.

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