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mutagen |
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mutagen: see mutation mutation, in biology, a sudden, random change in a gene , or unit of hereditary material, that can alter an inheritable characteristic. Most mutations are not beneficial, since any change in the delicate balance of an organism having a high level of adaptation to its ..... Click the link for more information. . mutagenAny agent capable of altering a cell's genetic makeup by changing the structure of the hereditary material, DNA. Many forms of electromagnetic radiation (e.g., cosmic rays, X rays, ultraviolet light) are mutagenic, as are various chemical compounds. The effects of some mutagens are increased or suppressed in some organisms by the presence of certain other, nonmutagenic substances; oxygen, for example, makes cells more sensitive to the mutagenic effects of X rays. mutagen a substance or agent that can induce genetic mutation How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The first major step is the elimination of all substances "teratogenic, mutagenic, carcinogenic, or otherwise harmful in direct and obvious ways to human and ecological health. The resulting mutagenic and wild-type products were cloned into the pGEM-T Easy Vectors (Promega, Madison, WI, USA), confirmed by direct sequencing, and then used as positive controls. The authors reported a selection bias, in which registrant-submitted studies on atrazine mutagenicity were all negative (no mutagenic activity), whereas over a dozen studies in the published literature reported mutagenic activity. |
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