mycosis fungoides


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mycosis fungoides

[mī¦kōs·əs fəŋ′gȯi‚dēz]
(medicine)
A lymphoma of the skin, usually present in several sites when first diagnosed, that may remain confined to the skin for 10 or more years before eventually spreading to internal organs and causing death.
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Detection of a peripheral blood T cell clone is an independent prognostic marker in mycosis fungoides.
marketing approval of its mechlorethamine gel for the treatment of early stage (stages I-IIA) mycosis fungoides, the most common type of Cutaneous T-Cell Lymphoma (CTCL).
The new management team will strengthen the company's foundation and drive momentum as it prepares the NDA submission for its propriety gel formulation of mechlorethamine hydrochloride for the treatment of early stage (stages I-IIA) mycosis fungoides, a type of Cutaneous T-Cell Lymphoma (CTCL).
Baseline characteristics presented at ICML show the average patient age to be 58 years with slightly more men enrolled in the registry to date [44 men (59%) and 30 female (41%)]; the most common PTCL subtypes are PTCL-NOS (18 of 74 patients; 24%), ALCL (13 of 74 patients; 18%), AITL (11 of 74 patients; 15%), T/NK cell lymphoma, nasal type (7 of 74 patients; 10 %), and transformed mycosis fungoides (7 of 74 patients; 10%).
Thirty-eight CTCL patients with Mycosis Fungoides (MF) were treated in these studies and 42% achieved at least a partial response, 30% at the 280 mg dose, 50% at 560 mg and 75% at 980 mg as measured by Composite Assessment of Index Lesion Disease Activity score.
Genmab announced positive Phase II data in HuMax-CD4 cutaneous T-cell lymphoma (CTCL) studies - 55% of higher dose patients treated for the primary indication, mycosis fungoides, achieved at least a partial response.
The objective of this retrospective subgroup analysis was to assess the activity and safety of single-agent FOLOTYN in patients enrolled in PROPEL who were diagnosed with histologically confirmed relapsed or refractory transformed mycosis fungoides (tMF), which is an aggressive and difficult to treat T-cell lymphoma.
Abstract #2544: Non-Myeloablative Allogeneic Transplantation Resulting in Clinical and Molecular Remission with Low Non-Relapse Mortality (NRM) in Patients with Advanced Stage Mycosis Fungoides (MF) and Sezary Syndrome (SS) Presenter: Wen-Kai Weng Session: 732.
Initially, lichen sclerosis et atrophicus, atrophoderma of Pasini-Pierini, sarcoidosis, mycosis fungoides, post-inflammatory hyperpigmentation were considered in the differential diagnosis of our case.
Ceptaris developed and secured FDA approvals in August for the gel Valchlor (mechlorethamine) for early stage mycosis fungoides, a type of cutaneous T-cell lymphoma.
Michael Krathen, MD, Clinical Assistant Professor of Dermatology at Stanford University, noted the ongoing clinical trial during a presentation at the annual meeting of the American Academy of Dermatology titled, "Case Based Discussions in Cutaneous Lymphomas: Treating early stage mycosis fungoides.