Myelocyte

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myelocyte

[′mī·ə·lə‚sīt]
(histology)
A motile precursor cell of blood granulocytes found in bone marrow.

Myelocyte

 

one of the types of cells in the hematopoietic tissue of the red bone marrow in vertebrate animals and in man. They are formed from hemocytoblasts and pass through the promyelocyte stage. Granular leukocytes, or granulocytes, develop from myelocytes. The nuclei of myelocytes are round or bean-shaped and less compact than in mature leukocytes; the cytoplasm is weakly basophilic. Myelocytes do not normally enter the bloodstream, but in certain pathological conditions, such as leukemia, they may appear in the blood.

References in periodicals archive ?
Characteristics of hematologic malignancy patients with URTI or LRTI and pandemic (H1N1) 2009 virus, University of California, San Francisco, Medical Center, San Francisco, California, USA, June-December 2009 * Total, URTI, Characteristic n = 27 n = 17 Median age, y (range) 43 (5-83) 33 (5-83) Male sex 18 (67) 10 (59) Underlying malignancy Acute lymphocytic leukemia 6 (22) 5 (29) Acute myelocytic leukemia 5 (19) 4 (24) Chronic lymphocytic leukemia 1 (4) 1 (6) Lymphoma 6 (22) 2 (12) Multiple myeloma 7 (26) 4 (24) Other 2 (7) 1 (6) Hematopoietic cell transplant 18 (67) 12 (71) Allogeneic 7 (39) 4 (33) Graft-vs.
Patient #17: In April 1977, after developing a scrotal abscess and significant anemia requiring transfusion, Patient #17 was diagnosed at the Ochsner Clinic in New Orleans with acute myelocytic leukemia, confirmed by bone marrow biopsy.
Three years ago, after a blood test before a bunion operation on her right foot, she eventually found out she had acute myelocytic leukemia, an aggressive, fast-moving from of the blood cancer.
However, myelocytic differentiation can take place in the presence of pharmacological rather than physiological levels of ATRA.
Unique genetic alterations in combinations or in isolation account for a small fraction of MDS suggesting the epigenetic hypermethylation as a possible leading cause for MDS and its transformation to acute myelocytic leukaemia (AML).
Abstract: Granulocytic sarcomas, also known as chloromas, are rare extramedullary tumors of myeloid or myelocytic origin.
Chronic myelocytic leukemia-Part II: Approaches to and molecular monitoring of therapy.
Significant tumor response to Hydrea has been demonstrated in melanoma, resistant chronic myelocytic leukemia; and recurrent, metastatic, or inoperable carcinoma of the ovary.
Initially approved in 2001, Glivec, a single transduction inhibitor, is now available in over 80 countries worldwide and is indicated for the treatments of chronic myelocytic leukemia and gastrointestinal stromal tumor.
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukemia.
s Cytosar-U and is indicated for remission induction in certain cases of patients with acute lymphocytic leukemia and chronic myelocytic leukemia.
Detection of BCR-ABL gene rearrangement and the elimination of rearranged clone in chronic myelocytic leukemia patients.