myelofibrosis


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myelofibrosis

[‚mī·ə·lō·fī′brō·səs]
(pathology)
Growth of white, fibrous connective tissue in the bone marrow.
References in periodicals archive ?
A multi-center, single-arm phase II trial (JAKARTA-2) evaluated fedratinib in myelofibrosis patients who were found to be resistant or intolerant to ruxolitinib (Jakafi), a JAK1/JAK2 inhibitor.
How control of myelofibrosis was apparently accomplished, with partial resolution of pancytopenia and complete elimination of the projected weekly transfusions for maintenance, is described and discussed below.
While the cause of myelofibrosis was being evaluated, the patient had an episode of loss of consciousness.
Efficacy of ruxolitinib in Korean myelofibrosis patients and cases complicated TB lymphadenitis during the treatment.
Without the first course of treatment in 2004 Eric would have been too weak to have surgery for a separate face cancer he suffered while battling myelofibrosis.
L, B5--No evidence of Myelofibrosis, B6--No evidence of Myelodysplatic syndrome.
The approval of Jakavi(R) by the Health Sciences Authority brings an urgently needed new treatment option to patients with myelofibrosis," said Dr.
The marrow findings, in conjunction with clinical findings, raised a few differential diagnostic possibilities: primary myelofibrosis, acute megakaryoblastic leukemia, or acute panmyelosis with myelofibrosis.
Patients and Methods: Ninety three consecutive patients of Polycythaemia vera (PV), Essential thrombocythaemia (ET) and Idiopathic myelofibrosis (IMF) diagnosed by the conventional haematological criteria were included in the study.
Food and Drug Administration ("FDA") approval for distribution and sale in the United States of its drug Jakafi (ruxolitinib), which is indicated for the treatment of patients with intermediate or high-risk myelofibrosis.
Myeloproliferative neoplasms (MPNs) (6) are a group of hematologic malignancies that include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF).
Polycythemia vera (PV), primary myelofibrosis (PMF), and essential thrombocythemia (ET) are the 3 classical Philadelphia chromosome-negative chronic myeloproliferative neoplasms (MPNs) that are characterized by clonal proliferation of multipotent hematopoietic progenitor cells.