inositol

(redirected from myo-inositol)
Also found in: Dictionary, Thesaurus, Medical, Acronyms.

inositol

(ĭnō`sĭtōl): see vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
..... Click the link for more information.
.

Inositol

The generic name for hexahydroxycyclohexanes, which are classified as carbohydrates. The inositols have exceptional chemical stability and are easily crystallized. Of the forms common in nature, the most ubiquitous and biologically important is myoinositol, a water-soluble crystalline compound. Many biological functions require myoinositol, and thus it is identified as an essential metabolite. Although originally classified as a vitamin, myoinositol is now known to be a cellular precursor of phospholipids that serve as a source of metabolic regulators and as membrane anchors for certain proteins. Some microorganisms require exogenous myoinositol for growth. See Carbohydrate, Lipid

Inositol

 

(hexahydroxycyclohexane), a cyclic hexatomic alcohol. It exists in nine possible stereoisomeric forms, of which only myoinositol (meso-inositol) exhibits vitamin properties.

Inositol is a sweet-tasting solid substance with a melting point of 225°–227°C and a molecular weight of 180.2. Readily soluble in water and insoluble in organic solvents, it is widely distributed in plants, generally in the form of phytic acid and its calcium-magnesium salt (Phytin). Inositol is an essential growth factor for certain microorganisms. The human daily requirement of inositol is approximately 1–1.5 g. Like choline, inositol exhibits lipotropic properties; in particular, it prevents adiposis of the liver when there is a protein deficiency in the diet.

inositol

[i′näs·ə‚tȯl]
(organic chemistry)
C6H6(OH)6·2H2O A water-soluble alcohol often grouped with the vitamins; there are nine stereoisomers of hexahydroxycyclohexane, and the only one of biological importance is optically inactive meso-inositol, comprising white crystals, widely distributed in animals and plants; it serves as a growth factor for animals and microorganisms.
References in periodicals archive ?
Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls.
Effect of juvenile hormone analogs on diapause termination and myo-inositol content in Aulacophora nigripennis (Coleoptera Chrysomelidae).
Development of an immunoassay for the kidney-specific protein myo-inositol oxygenase, a potential biomarker of acute kidney injury.
Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-henethylthiocarbamoyl)-l-cysteine and myo-inositol, individually and in combination.
Myo-inositol (mI) was significantly increased in the occipital gray matter in apnoeics in our study.
In the form of myo-inositol hexaphosphate (IP6), the phosphate groups at positions 1, 2 and 3 specifically interact with free iron to completely inhibit the formation of hydroxyl radicals, hence phytate's antioxidant power.
Though the substance is not natural, it is said to be related to myo-inositol, which is found in rice and cereals.
Psychiatrists at King's College, London, say myo-inositol makes Down's sufferers retarded.
They measured the ratio of n-acetylaspartate to creatine and the ratio of myo-inositol to creatine.
Reduced levels of n-acetylaspartate are thought to result from nerve cell dysfunction and loss; increased myo-inositol levels are thought to be due to increased inflammation.
43 ppm in the ratio 1:2:2:1 were identified by spectral deconvolution and assigned to myo-inositol hexakisphosphate (I[P.