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nalidixic acid

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nalidixic acid [¦nal·ə¦dik·sik ′as·əd]
(pharmacology)
C12H12N2O3Pale buff, crystalline powder; melting point is 229-230°C; soluble in chloroform and in potassium hydroxide and sodium hydroxide solutions; used as an antibacterial drug in humans and animals.


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Until 2002, all Salmonella isolates worldwide with reduced ciprofloxacin susceptibility were uniformly resistant to nalidixic acid (3-5); i.
Greater selectivity with pure cultures and food samples is achieved by blending acriflavine and nalidixic acid components into the base powder and adding ferric ammonium citrate (X211) to the tempered broth after autoclaving.
90] values of nalidixic acid were very high and the remaining antibiotics were within range (Table 3).
 
 
 
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