naltrexone


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naltrexone

[nal′trek‚zōn]
(pharmacology)
C20H23NO4 An opiate receptor antagonist that blocks the effects of endogenous opioids in the brain; used to treat alcoholism.
References in periodicals archive ?
In another study, the COMBINE trial, which found a "robust" effect of treatment with naltrexone over placebo among those with the Asp40 allele, "naltrexone seemed to be moderated by the presence of the Asp40 allele," with "essentially no effect" of naltrex one in the homozygous (Asn40/Asn40) group, he noted (Arch.
Naltrexone treatment, in any form, is also very different from Methadone treatment in that Naltrexone is not addictive," said (http://finance.
Clinicians and patients therefore should use factors other than effectiveness to choose between acamprosate and oral naltrexone, such as the local availability of the drug, convenience of dosing, cost, adverse-event profile, and contraindications, Dr.
It found that even though extended-release Naltrexone is expensive - about $1,100 a month - total health care costs were generally lower for patients taking it, compared to those using other alcohol and drug-dependence treatments.
With research governance ethics approval, we searched the operating theatre management system database to identify patients who had presented for removal of naltrexone implants between 1 January 2001 and 31 December 2008.
Naltrexone was significantly more effective in reducing the rate of heavy drinking than placebo, an effect most pronounced in those who had achieved abstinence prior to receiving the first injection.
While acamprosate and naltrexone have been designed to address cravings, their effectiveness has been uneven.
Low-dose naltrexone for the treatment of irritable bowel syndrome: a pilot study [abstract].
CAMPAIGN: MS sufferer Andrew Barnett, who wants low-dose Naltrexone trialled, with his partner, Jayne Cocker at home near Gorseinon PICTURE: Dimitris Legakis
As a generic drug with no close therapeutic substitutes in the treatment of alcohol dependency, naltrexone should be a widely available treatment option.
Compared with the placebo patients, patients given the higher dose of naltrexone had significant reduction in the average daily number of drinks consumed by the second day.
NEW ORLEANS -- Combination therapy with bupropion and naltrexone resulted in superior weight loss, compared with placebo or either drug alone, Dr.