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naproxen
(redirected from naproxen sodium)

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naproxen and naproxen sodium, potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever. Along with ibuprofen ibuprofen (ī`by
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 and ketoprofen ketoprofen (kē'təprō`fĭn)
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, they belong to the propionic acid class of NSAIDs. They have been available as prescription drugs for arthritis from 1976. Naproxen sodium was approved at a low dosage as an over-the-counter painkiller in the United States in 1994; it was first marketed under the tradename Aleve. Side effects may include gastrointestinal distress and dizziness, and renal impairment has been reported in some instances with long-term use. The drugs should not be used by those who are allergic to aspirin aspirin, acetyl derivative of salicylic acid (see salicylate ) that is used to lower fever, relieve pain, reduce inflammation, and thin the blood. Common conditions treated with aspirin include headache, muscle and joint pain, and the inflammation caused by rheumatic
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It is a patented sequential release tablet containing two approved drugs, naproxen sodium, which relieves pain and reduces inflammation, and metoclopramide, which accelerates the absorption of naproxen and contributes to the relief of migraine.
Food and Drug Administration (FDA) for the marketing approval of Trexima(TM), the proposed brand name for the combination of sumatriptan succinate, formulated with RT Technology (TM), and naproxen sodium, in a single tablet for the acute treatment of migraine.
The Advisory Committee voted that the potential, but unquantified, risk for tardive dyskinesia would outweigh the benefits, as defined by the FDA, of metoclopramide hydrochloride in combination with naproxen sodium.
 
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