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Necrobiosis
(redirected from necrobiotic)

    Also found in: Dictionary/thesaurus, Medical 0.01 sec.
necrobiosis [¦ne·krō‚bī′ō·səs]
(medicine)
Death of a cell or group of cells under either normal or pathologic conditions.
Necrobiosis 

the change that occurs in a cell prior to cell death. Necrobiosis is linked with metabolic disturbances that may lead to fatty degeneration or to other types of degeneration in the cell. These degenerative changes can be reversible. The most typical symptoms of necrobiosis are changes in the cell nucleus, such as karyopyknosis, karyorrhexis, and karyolysis; disturbances in the viscosity of the cytoplasm; an abnormal staining reaction; and disorganization of the enzyme systems of the cell, which leads to cellular autolysis.
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It is characterized by necrobiotic changes in the dermis that extend down to the perichondrium; associated alterations are seen in the cartilaginous plate.
Chondrodermatitis nodularis helicis by Thompson, Lester D.R. / Ear, Nose and Throat Journal
69) Colloidal iron or Alcian blue stains may reveal mucin in the central necrobiotic foci of granuloma annulare, (70) but in our experience that finding is not typical of ES.
Selected diagnostic problems in neoplastic dermatopathology by DiCaudo, David J.; McCalmont, Timothy H.; Wick, Mark R. / Archives of Pathology & Laboratory Medicine
Evans CS, Goldman RL, Klein HZ, et al: Necrobiotic granulomas of the uterine cervix.
Incidental granulomatous inflammation of the uterus by Prayson, Richard A. / Southern Medical Journal
 
 
 
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