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toxic epidermal necrolysis
(redirected from necrolysis)

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toxic epidermal necrolysis [¦tak·sik ‚ep·ə‚dər·məl nə′kräl·ə·səs]
(medicine)
Intraepidermal blistering and separation of the outer epidermis, giving the appearance and the management problems of a scald, caused by infection withStaphylococcus aureusstrains producing one of the epidermolytic toxins, usually of phage group II. Also known as scalded skin syndrome.


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Viard I, Wehrli P, Bullani R et al: Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.
Cases of carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported among carriers of this allele (Pharmacogenomics 2008; 9: 1543-6).
Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis in children: a review of 10 years' experience.
 
 
 
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