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neomycin

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neomycin (nē'ōmī`sĭn), broad spectrum antibiotic antibiotic, any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms.

Types of Antibiotics


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 effective against both gram positive and gram negative bacteria (see Gram's stain Gram's stain, laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls.
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). It interferes with protein synthesis in sensitive bacterial cells such as species of Proteus and Staphylococcus. Neomycin is mainly used topically in the treatment of skin and mucous membrane infections, wounds, and burns. Although it is also used systemically, it is highly toxic. Neomycin was first isolated in 1949 by the American microbiologist Selman Waksman from a strain of the bacterial species Streptomyces fradiae.

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Finally, we don't know what the outcomes would have been if an aminoglycoside other than neomycin had been used.
In addition, both strains were found to be d-tartrate-fermenting (dT+) biovars (4), susceptible to ampicillin, amoxicillin-clavulanic acid, cephalothin, ceftazidime, gentamicin, streptomycin, chloramphenicol, tetracycline, neomycin, nalidixic acid, norfloxacin, and ciprofloxacin and resistant to sulfamethoxazole and co-trimoxazole.
Neomycin and Polymyxin B Sulfates and Gramicidin Ophthalmic Solution
 
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