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neuropeptide |
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neuropeptide [‚nu̇r·ō′pep‚tīd] (neuroscience) A polypeptide released by axons at the synapse; it may act as a neurotransmitter and have a direct effect on synapse function or as a neuromodulator, having a long-term effect on postsynaptic neurons. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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S-2367 is a small molecule, oral, once-daily neuropeptide Y (NPY) Y5 receptor antagonist discovered by Shionogi Research Laboratories. In the airway, a dense network of sensory nerve fibers is strategically placed just below the epithelial surface, so that any change in the bronchial environment may stimulate the release of the proinflammatory neuropeptide substance P (Piedimonte 1995). The protein could lead to drugs for narcolepsy, sleepiness, or anxiety, suggest its discoverers, who dubbed the chemical neuropeptide S. |
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