neurotoxicity

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neurotoxicity

[‚nu̇·ro·täk′sis·əd·ē]
(medicine)
Adverse effects on the structure or function of the central and/or peripheral nervous system caused by exposure to a toxic chemical, symptoms include muscle weakness, loss of sensation and motor control, tremors, cognitive alterations, and autonomic nervous system dysfunction.
References in periodicals archive ?
UCLA researchers proposed that molecular mechanisms behind each disability may differ, and that neuroprotective treatments tailored for each disability may be more effective than nonspecific treatments aiming to reduce a composite of different disabilities.
Director of clinical development at Herantis, Sigrid Booms, said: "CDNF is a novel neurotrophic and neuroprotective factor, which affects several mechanisms relevant to Parkinson's disease.
There are, in fact, many off-label supplements with strong neuroprotective effects that psychiatrists can use as an adjunct to standard evidence-based pharmacotherapy.
Moderate neuroprotective effects of 5 mg/kg p-tyrosol administration were documented only at day 5 after GCI.
Pathomechanisms of diseases are described with steps at which neuroprotective therapies are directed.
This trial had avery small sample size which limits the interpretation of results for a larger group of population but this provides a solid ground for future studies in evaluating the efficacy of GCSF as neuroprotective and repair agent for stroke patients.
In addition, this new research indicates that it may be neuroprotective.
Discussion: Topical [alpha]-tocopherol has a significant neuroprotective effects in optic nerve crush model of rat and may be used in the future for the treatment of optic neuropathies such as glaucoma.
Mice with a condition that serves as a laboratory model for Down syndrome perform better on memory and learning tasks as adults if they were treated before birth with neuroprotective peptides, according to researchers at the National Institutes of Health.
The research has turned up clues to a neuroprotective mechanism that could lead to a treatment for Alzheimer's disease.