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neurotransmitter
(redirected from neurotransmissions)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.04 sec.
neurotransmitter, chemical that transmits information across the junction (synapse synapse (sĭn`ăps), junction between various signal-transmitter cells, either between two neurons or between a neuron and a muscle or
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) that separates one nerve cell (neuron) from another nerve cell or a muscle. Neurotransmitters are stored in the nerve cell's bulbous end (axon). When an electrical impulse traveling along the nerve reaches the axon, the neurotransmitter is released and travels across the synapse, either prompting or inhibiting continued electrical impulses along the nerve. There are more than 300 known neurotransmitters, including chemicals such as acetylcholine acetylcholine (əsēt'əlkō`lēn), a small organic molecule liberated at nerve endings as a neurotransmitter .
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, norepinephrine norepinephrine (nôr'ĕpīnĕf`rən)
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, adenosine triphosphate adenosine triphosphate (ATP) (ədĕn`əsēn trī'fŏs`fāt)
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, and the endorphins endorphins (ĕndôr`fĭnz), neurotransmitters found in the brain that have pain-relieving properties similar to morphine.
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, and gases, such as nitric oxide nitric oxide or nitrogen monoxide, a colorless gas formed by the combustion of nitrogen and oxygen as given by the reaction: energy + N2 + O2 → 2NO; m.p. −163.6°C;; b.p. −151.8°C;.
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. Neurotransmitters transmit information within the brain and from the brain to all the parts of the body. Acetylcholine, for example, sends messages to the skeletal muscles, sweat glands, and heart; serotonin serotonin (sĕr'ətō`nĭn), organic compound that was first recognized as a powerful vasoconstrictor occurring in blood serum.
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 release underlies the process of learning and consciousness.

The actions of some drugs mimic those of naturally occurring neurotransmitters. The pain-regulating endorphins, for example, are similar in structure to heroin and codeine, which fill endorphin receptors to accomplish their effects. The wakefulness that follows caffeine consumption is the result of its blocking the effects of adenosine, a neurotransmitter that inhibits brain activity. Abnormalities in the production or functioning of certain neurotransmitters have been implicated in a number of diseases including Parkinson's disease Parkinson's disease or Parkinsonism, degenerative brain disorder first described by the English surgeon James Parkinson in 1817. When there is no known cause, the disease usually appears after age 40 and is referred to as Parkinson's disease.
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, amyotrophic lateral sclerosis amyotrophic lateral sclerosis (ALS) (ā'mīətrōf`ik, sklĭrō`sĭs) or
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, and clinical depression depression, in psychiatry, a symptom of mood disorder characterized by intense feelings of loss, sadness, hopelessness, failure, and rejection. The two major types of mood disorder are unipolar disorder, also called major depression, and bipolar disorder, whose
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.


neurotransmitter

Chemical released by neurons to stimulate neighbouring neurons, allowing impulses to be passed from one cell to the next throughout the nervous system. A nerve impulse arriving at the axon terminal of one neuron stimulates release of a neurotransmitter, which crosses the microscopic gap (see synapse) in milliseconds to the adjoining neuron's dendrite. Many chemicals are believed to act as neurotransmitters. The few that have been identified include acetylcholine, dopamine, and serotonin. Some neurotransmitters activate neurons; others inhibit them. Some mind-altering drugs act by changing synaptic activity.


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Huperzine-A is believed to inhibit acetylcholinesterase and enhance cholinergic neurotransmissions.
 
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