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neutralization reaction

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
neutralization reaction [‚nü·trə·lə′zā·shən rē‚ak·shən]
(chemistry)

Neutralization reaction (immunology)

A procedure in which the chemical or biological activity of a reagent or a living organism is inhibited, usually by a specific neutralizing antibody. As an example, the lethal or the dermonecrotic actions of diphtheria toxin on animals may be completely neutralized by an equivalent amount of diphtheria antitoxin.

Antibodies to bacterial, snake-venom, and other enzyme preparations regularly precipitate them from solution so that the supernates are devoid of enzyme activity; however, the neutralization of activity in the precipitate may range from complete to negligible. See Immunology, Serology



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