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Prolonged administration of antibiotics in neutropenic patients can predispose them to an increased risk of: a.
In this study we showed that a dynamic assessment of the risk of IMD using the D-index may be of help to decide whether antifungal therapy should be given to neutropenic patients.
Bacteremia due to viridans streptococcus in neutropenic patients with cancer: clinical spectrum and risk factors.
Neutropenic enterocolitis (NE), ileocaecal syndrome, agranulocytic colitis or necrotizing enterocolitis is a rare phenomenon seen in neutropenic patients.
Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america.
The mean CD4 count in the neutropenic HIV-infected patients was 378 cells/[micro]L (range 80-708), compared with 509 cells/[micro]L (range 245-945) in the non-neutropenic group.
The PRAC has concluded that there is no evidence of a change in the known risk of neutropenic enterocolitis in the European Union (EU) after treatment with docetaxel, a cancer medicine.
After they entered the neutropenic period, all allo-HSCT patients were treated with fluconazole (Zolax; Sanovel, Sariyer, Istanbul, Turkey) 400 mg/day until day +75, valacyclovir (Valtrex; Glaxo Smith Kline Turkey, Levent, Istanbul, Turkey) 1000 mg/day until day +90 and trimethoprim (TMP) - sulfamethoxazole (SMX) (Bactrim Fort; Deva, Kucukcekmece, Istanbul, Turkey) (320 mg/week TMP equivalent) until day +180.
Prophylaxis with fluoroquinolones for bacterial infections in neutropenic patients: a metaanalysis.
Conclusion: In adult patients, septic shock, severe ARDS, history of chronic liver disease, neutropenic sepsis and presence of HIV, and invasive mechanical ventilation are associated with a higher risk of ICU mortality in patients admitted with severe pneumonia.
Patients being treated for underlying leukemia or lymphoma may rarely present with neutropenic colitis (typhilitis) as an acute complication.
Active surveillance by early detection, isolation of the patients and better compliance with hand hygiene can help reduce the spread of such infections among already compromised neutropenic cancer patients.