Neutrophil


Also found in: Dictionary, Thesaurus, Medical, Financial, Wikipedia.
Related to Neutrophil: hypersegmented neutrophil

neutrophil

[′nü·trə‚fil]
(histology)
A large granular leukocyte with a highly variable nucleus, consisting of three to five lobes, and cytoplasmic granules which stain with neutral dyes and eosin.

Neutrophil

 

(also called polymorphonuclear neutrophil leukocyte, microphage), a type of white blood cell, or leukocyte, occurring in vertebrates and man. The diameter of a neutrophil ranges from 9 to 12 μ. The cytoplasm of these cells contains granules that attract both basic and acidic dyes, and this is why these leukocytes are called neutrophils.

A neutrophil is classified according to its degree of maturity: a metamyelocyte is a young neutrophil with an unsegmented nucleus, a rod neutrophil has a nucleus in the shape of a curved rod, and segmented, or filamented, neutrophils have segmented nuclei. Neutrophils are phagocytes that are capable of ingesting small foreign particles, including microbes. By elaborating hydrolytic enzymes, neutrophils can lyse dead tissue. Neutrophilia is an abnormal increase in the concentration of neutrophils in the blood. (SeeLEUKOCYTOSIS.)

References in periodicals archive ?
Frenette reported in 2002 that SCD vessel blockages occur when sickled red cells bind to white cells called neutrophils that have adhered to the vessel walls.
That chemical mixture triggers neutrophil migration - and researchers can automatically track and analyze the neutrophil chemotaxis velocity using custom software.
The blood samples (20 mL) were collected in heparinized tubes from all the animals at one week before expected calving to four weeks post-calving period at weekly interval for total leucocytes and neutrophil, lymphocyte counts, neutrophil functions and PBMCs culture for cytokines assay.
A web-like network called Neutrophils Extracellular Traps (NETs), is produced by white blood cells (neutrophils) in response to an infection and this normally traps and kills invading pathogens, such as bacteria.
The model reveals how the immune system functions under conditions of neutropenia--a dangerously how level of white blood cells, mainly neutrophils.
Quantitative determination of neutrophil VCS parameters by the Coulter automated hematology analyzer: new and reliable indicators for acute bacterial infection.
In addition, dying neutrophils, through a process known as NETosis, release neutrophil extracellular traps (NETs).
Acute bacterial and viral infections often trigger serious asthma attacks that result in hospitalization, and many of these patients have elevated levels of neutrophils in their airways.
Scientists at the Max Planck Institute of Neurobiology in Martinsried have now discovered a new serine protease: neutrophil serine protease 4, or NSP4.
Method: The effect of subcutaneous mistletoe therapy in 231 patients on leukocytes, neutrophils and lymphocytes is compared with that of 19 intravenous applications and complemented with the effects of the concurrent humoral reaction in the patients' serum.