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nitric oxide synthase

   Also found in: Acronyms, Wikipedia 0.04 sec.
nitric oxide synthase [‚nī·trik ¦äk‚sīd ¦sin‚thās]
(biochemistry)
An enzyme that catalyzes the stepwise conversion of the amino acid L-arginine to nitric oxide and L-citrulline. There are three types: the brain (or neuronal) and epithelial nitric oxide synthases, which are always present in cells, and inducible nitric oxide synthase, which is produced as needed.


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We analyzed data on three such genetic polymorphisms: [delta-aminolevulinic acid dehydratase (ALAD), endothelial nitric oxide synthase (eNOS), and the vitamin D receptor (VDR).
Nitric oxide (NO), a gas that was once believed to present only in the atmosphere, is produced in human tissues by the enzyme nitric oxide synthase (NOS), with L-arginine as the substrate.
This reduced concentrations of two inflammatory agents--inducible nitric oxide synthase and cyclooxygenase-2, or COX-2.
 
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