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C6H5NO2, very poisonous, flammable, pale yellow, liquid aromatic compound with an odor like that of bitter almonds. It is sometimes called oil of mirbane or nitrobenzol. Nitrobenzene melts at 5.85°C;, boils at 210.9°C;, is only slightly soluble in water, but is very soluble in ethanol, ether, and benzene. It is prepared by treating benzene with a mixture of nitric and sulfuric acids; in the resulting nitration reaction, one hydrogen in the benzene molecule is replaced with a nitro group, NO2. The major use of nitrobenzene is in the production of anilineaniline
, C6H5NH2, colorless, oily, basic liquid organic compound; chemically, a primary aromatic amine whose molecule is formed by replacing one hydrogen atom of a benzene molecule with an amino group.
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, commercially the most important amine; nitrobenzene is heated with iron and dilute hydrochloric acid, and the resulting anilinium chloride is treated with sodium carbonate to release aniline. In the pharmaceutical industry nitrobenzene is used in the production of the analgesic acetaminophenacetaminophen
, an analgesic and fever-reducing medicine. It is an active ingredient in many over-the-counter medicines, including Tylenol and Midol. Introduced in the early 1900s, acetaminophen is a coal tar derivative that acts by interfering with the synthesis of
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, or paracetamol. Nitrobenzene is also used in shoe and floor polishes, leather dressings, and paint solvents to mask unpleasant odors. As oil of mirbane, nitrobenzene was used as an inexpensive perfume for soaps and cosmetics but is now considered too toxic for such applications.



C6H5NO2, the simplest aromatic nitro compound; an oily light yellow liquid. Melting point, 5.7°C; boiling point, 210.9°C; density, 1.987 g/cm3 at 25°C. It is poorly soluble in water but mixes well with organic solvents.

Upon reduction, nitrobenzene is converted to aniline or hydrazobenzene, depending on the conditions. Under the action of acids, hydrazobenzene isomerizes to benzidine. Nitration, sulfonation, and chlorination of nitrobenzene take place mainly at the meta- position to the nitro group, for example:

Nitrobenzene is produced by nitration of benzene by a nitrating mixture. It is poisonous, with a maximum permissible concentration in air of 3 mg/m3 in work areas and 0.008 mg/m3 in residential buildings.

Nitrobenzene is mainly used in the production of aniline. In small quantities, nitrobenzene is also used in the production of intermediates for dyes (methanilic acid and benzidine), and also certain dyes (for example, induline).


Orlova, E. Iu. Khimiia i tekhnologiia brizantnykh vzryvchatykh ve-shchestv. Leningrad, 1973.


(organic chemistry)
C6H5NO2 Greenish crystals or a yellowish liquid, melting point 5.70°C; a toxic material; used in aniline manufacture. Also known as oil of mirbane.
References in periodicals archive ?
IR-spectra were measured, using KBr disc on a matson 5000 FTIR-spectrometer molar conductivities in nitrobenzene were measured on Toshniwal conductivity bridge.
Surface modification of TiO2 nanoparticles for photochemical reduction of nitrobenzene.
The response of PEDOT:PSS/NGP NCs film for vapors of nitrobenzene were measured using conventional resistance measurement methods by placing the sensor inside the gas chamber and exposing to vapors.
rate of addition, molar ratio of Aniline / Nitrobenzene, mole ratio of Nitrobenzene / base, pressure, air/ oxygen feed rate etc.
In addition to the analytical part, the report provides a range of tables and figures which all together give a true insight into the national, regional and global markets for nitrobenzene.
Particular emphasis is placed on the main application areas of benzene: ethylbenzene, cumene, cyclohexane, alkylbenzene, and nitrobenzene.
The technology consists of an 85-tonne, 23-metre reactor that converts raw materials, nitrobenzene and hydrogen, into aniline.
The 80-kilometer slick of water polluted with benzene and nitrobenzene reached Harbin, the capital of Heilongjiang Province, on Thursday morning.
According to Chinese experts, the concentration of benzene and nitrobenzene was perceptibly reduced over the past several days, and now their concentration exceeds the normal level only by two to four times,'' the Russian news agency said.
It has been demonstrated that Fenton's reagent is able to destroy different phenols, nitrobenzene, and herbicides in water media as well as to reduce COD in municipal wastewater [17-20].
The addition of nitrobenzene, for instance, slows both stages but appears to have no effect on how the degradation occurs.