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novobiocin

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.02 sec.
novobiocin [‚nō·və′bī·ə·sən]
(microbiology)
C30H36O11N2A moderately broad-spectrum antibiotic produced by strains ofStreptomyces niveusandS. spheroides; it is a dibasic acid and is converted either to the monosodium salt or to the calcium acid salt for pharmaceutical use.


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? Mentioned in ? References in periodicals archive
 
coli medium broth containing novobiocin (final concentration, 20 [micro]g/mL).
Home-prepared hamburger and sporadic hemolytic uremic syndrome, ... by Estani, Sergio Sosa / Emerging Infectious Diseases
Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptococcus pneumoniae is implicated in novobiocin resistance.
Antimicrobial susceptibility breakpoints and first-step parC ... by Low, Donald E. / Emerging Infectious Diseases
Swabs were then incubated overnight at 42 [degrees] C in 10 ml of mEC broth (Kyokuto, Japan) containing 20 [micro]g/ml of novobiocin (Sigma, USA), after which one loop of the broth was spread onto MacConkey sorbitol agar medium (Difco, USA).
Swine as a potential reservoir of Shiga toxin-producing Escherichia ... by Sameshima, Toshiya / Emerging Infectious Diseases
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