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nucleoprotein

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nucleoprotein

Macromolecular complex consisting of a protein linked to a nucleic acid, either DNA or RNA. The proteins that combine with DNA are generally of characteristic types called histones and protamines. The resulting nucleoproteins (deoxynucleoproteins) make up the chromosomes of living cells. Many viruses are little more than organized agglomerations of deoxynucleoproteins. Many specific RNA nucleoproteins are also known; they have diverse cellular functions.


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Genetic polymorphism in the rabies virus nucleoprotein gene.
However, eukaryotic cells contain an additional level of information superimposed on the DNA double helix in the form of a complex nucleoprotein entity generically termed "chromatin.
In 1993, the Merck researchers showed that a plasmid containing the gene for the internal nucleoprotein (NP) of influenza evoked an immune response to a different strain of the influenza virus in mice.
 
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